Education

2014-2020               

Stanford University, Stanford, CA                                             

Doctorate in Cancer Biology, 2020

• 2018-2020: National Institutes of Health/ National Cancer Institute (NIH/NCI) Predoctoral to Postdoctoral Transition Award (F99/K00) Fellow

• NIH/NCI National Research Service Award (NRSA, F31) recipient

• National Science Foundation (NSF) Graduate Research Fellow

2009-2012 

University of Pennsylvania, Philadelphia, PA                               

Bachelor of Arts with Honors in Biology and in Visual Studies

• Summa cum laude

• Phi Beta Kappa member

• Recipient of the Charles Willson Peale prize for excellence on the Visual Studies thesis

Work History

2023- Present

Medical Writer                        

PRECISIONscientia

• Developed scientific communication materials for large pharmaceutical industry clients, including conference presentations, internal and external training materials, medical education materials, congress posters, abstracts, manuscripts, symposiums, key opinion leader (KOL) insight reports, among others

• Facilitated planning, designed materials, and wrote executive summaries for KOL advisory board meetings 

• Designed and developed branded and unbranded medical content 

• Interfaced with clients to present and refine materials 

• Worked as part of a highly collaborative team to facilitate the launch of a new administration route for the client's approved drug 

2020-Present

Mentor, Polygence Research Academy

• Mentored 18 students one-on-one to guide them through independent projects including research proposals, academic review articles, popular science blogs, and research papers on topics such as cancer biology, biochemistry, and immunology

• Taught research skills including reading and evaluating scientific literature, managing citations, constructing bibliographies, note-taking, and communication skills

• Mentored 5 students who published projects in academic journals or presented projects at scientific symposiums

2020-2023

NIH/NCI F99/K00 Postdoctoral Fellow                             

Children’s Medical Center Research Institute

University of Texas, Southwestern Medical Center

Howard Hughes Medical Institute

• Led independent projects investigating the role of lipid metabolism in melanoma and amino acid metabolism in renal cell carcinoma

• Analyzed and visualized large and small-scale datasets for publications and oral presentations

• Co-authored manuscripts published in Nature and Science Advances

• Founded and organized a monthly Metabolism Journal Club attended by 6 labs and 30+ trainees

• Co-chaired the NIH/NCI F99/K00 Monthly Seminar attended by 50+ trainees

• Assisted with the writing and editing of 3 NIH grant applications

• Wrote science outreach materials for blogs and social media

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2014-2020

Doctoral Fellow                                                                 

Laboratory of Scott Dixon

Stanford University

• Led an independent research project to identify a role for the p53 tumor suppressor gene in non-apoptotic cell death

• Wrote and published 2 primary manuscripts in Cell Reports and Life Science Alliance, a textbook chapter for Ferroptosis in Health and Disease, and 2 news-style articles in Nature Nanotechnology and Oncotarget

• Wrote and received 3 fellowships from the NIH and NSF totaling over $600,000

• Supervised and mentored 5 students in wet lab and research skills

• Co-taught and developed course materials for CBIO240: Molecular and Genetic Basis of Cancer, a graduate level course for 20+ doctoral students

• Served on the Cancer Biology Program graduate admissions committee

2014-2020

Oral Communication Tutor                                                        

Hume Center for Writing and Speaking

Stanford University

• Mentored 500+ undergraduates, graduate students, and postdocs in oral communication

• Conducted 100+ mock interviews, including case interviews and chalk talks

• Led 10+ seminars on scientific communication for high schoolers, undergraduates, and graduate students

• Led 20+ seminars and break-out sessions for undergraduate classes in the Program in Writing and Rhetoric

2018 – 2019

Co-Chair of the Graduate Student Council                                            

Stanford University

• Successfully advocated for improvements in graduate student access to mental health services, leading to hiring of additional clinical staff and increased funding for wellness initiatives

• Negotiated and interfaced with university leaders including the Vice Provosts, President and members of the Board of Trustees to guide university policy

• Organized 2 town hall meetings on graduate student affordability and mental health

• Organized and led a mental health working group, co-authored policy proposals for improvements in student health services

2012-2014

Research Technician II                                                                             

Laboratory of Patrick Viatour

Children’s Hospital of Philadelphia, University of Pennsylvania

• Led an independent research project investigating the role of the Rb tumor suppressor family in hepatocellular carcinoma

• First author of a manuscript published in Nature Communications

• Oversaw the launch of the lab, managed lab operations and organization, handled ordering and inventory, trained 3 technical staff members

• Assisted with the writing and editing of 5+ grant proposals

​

2010 – 2012

Undergraduate Research Assistant                                                            

Laboratory of Dr. Paula Oliver

Children’s Hospital of Philadelphia, University of Pennsylvania

• Collaborated with a graduate student on a project investigating the role of the gut microbiota in T cell activity and function

• Co-first author of a manuscript published in PLoS One

Scientific Publications

Rodencal J, Kim N, Li V, He A, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann J, Sage J, Long JZ, Dixon SJ (2023) A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2. In review. 

Tarangelo A, Kim JT, Long JZ, Dixon SJ. Nucleotide metabolism regulates ferroptosis susceptibility in cancer cells. (2022) Life Science Alliance (5) 4

Solmonson A, Faubert B, Gu W, Rao A, Cowdin MA, Menendez-Montes I, Kelekar S, Rogers TJ, Pan C, Guevara G, Tarangelo A, ... Morrison SJ, DeBerardinis RJ. (2022) Compartmentalized metabolism supports midgestation mammalian development. Nature. 604 (7905), 349-353

Kaushik, AK., Tarangelo, A., ... DeBerardinis, RJ. (2022) In-vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science Advances. 8(50)

Valente LJ, Tarangelo A, Li AM, Maciri M, Raj N, Boutelle AM, Li Y, Mello SS, Bieging-Rolett K, DeBerardinis RJ, Ye J, Dixon SJ, Attardi LD. (2020) p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen. Journal of Cell Biology. 219(11)

Magtanong L, Ko P-J, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho KY, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ. (2019). Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state. Cell Chemical Biology. 26, 1-13.

Tarangelo A, Dixon, SJ. (2019) Lipid metabolism and ferroptosis. Ferroptosis in Health and Disease 1st Ed. Ed: Tang, D. 1-26. (Textbook Chapter)

Tarangelo A, Magtanong L, Li Y, Bieging-Rolett K, Yi J, Attardi LD, Dixon SJ. (2018). p53 suppresses metabolic stress-induced ferroptosis in cancer cells. Cell Reports. 22(3), 569-575.

Tarangelo A & Dixon SJ (2018) The p53-p21 pathway inhibits ferroptosis during metabolic stress. Oncotarget. 9(37), 24572 (Self-Commentary).

Kim E, Cheng Y, Bolton-Gillespie E, Cai X, Ma C, Tarangelo A, ... Viatour P. (2017). Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. J. Exp. Med. 214 (7), 1901-1912.

Tarangelo A & Dixon SJ. (2016). Nanomedicine: An iron age for cancer therapy. Nature Nanotech. 11(11), 921. (Review article)

Tarangelo A, Lo N, Teng R, Kim E, Le L, Watson D, Furth EE, Raman P, Ehmer U, Viatour P. (2015). Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Nature Communications, 6, 10028.

Kurzweil V*, Tarangelo A*, Oliver PM. (2012). Gastrointestinal microbiota do not significantly contribute to T cell activation or GI inflammation in Ndfip1-cKO mice. PLoS One, 7(4). e34478. *Co-first authors

Academic Awards

2020

NIH/NCI Predoctoral to Postdoctoral Transition Award, K00 Phase

Grant number 4K00CA234650-03

2018

NIH/NCI Predoctoral to Postdoctoral Transition Award Recipient (F99/K00)

Grant number 1F99CA234650-01

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NIH/NCI National Research Service Award Predoctoral Fellowship (F31)

Grant Number 1F31CA232699-0

​

2017

Oral Presentation Award

Fusion Conference on Cell Death, Cell Stress and Metabolism, Cancún, Mexico

​

2016

Oral Presentation Award

Stanford Cancer Biology Annual Program Retreat, San Jose, CA

2015

National Science Foundation Graduate Research Fellowship Recipient

2012

Phi Beta Kappa Society Member

Delta Chapter, University of Pennsylvania

​

Charles Willson Peale Prize Recipient

Awarded for excellence on the Visual Studies thesis project

Dept. of Visual Studies, University of Pennsylvania

Academic Presentations

2021

Tarangelo A, Tasdogan A, Morrison SJ, DeBerardinis RJ. Investigating the role of sphingolipid metabolism in melanoma metastasis. (August 12, 2021). NIH/NCI F99/K00 Fellows Meeting, Virtual (Poster presentation)

2020

Tarangelo A. Death Metal: The p53-p21 pathway at the crossroads of survival and iron-dependent cell death (January 16th, 2020). Stanford, CA. (Thesis Defense Presentation)

2019

Tarangelo A, Magtanong, L. , Li, Y., Ye, J., Attardi, LD., Dixon, SJ. The p53-p21 pathway suppresses non-apoptotic cell death through metabolic rewiring. (November 11th 2019) Stanford Cancer Biology 42nd Annual Retreat. San Jose, CA. (Poster presentation)

Tarangelo A, Magtanong L, Bieging-Rolett K, Li Y, Ye J, Attardi LD, Dixon, SJ. The p53-p21 axis suppresses metabolic stress-induced ferroptosis. (January 11th, 2019). NIH/NCI F99/K00 Fellows Meeting, Bethesda, MD. (Poster presentation)

2018

Tarangelo A, Magtanong L, Bieging-Rolett K, Li Y, Ye J, Attardi LD, Dixon, SJ. The p53-p21 axis suppresses metabolic stress-induced ferroptosis. (Sept. 30th, 2018). AACR Special Conference on Metabolism and Cancer, New York, NY. (Oral and poster presentations)

Tarangelo A, Magtanong L, Bieging-Rolett K, Li Y, Ye J, Attardi LD, Dixon, SJ. The p53-p21 axis suppresses metabolic stress-induced ferroptosis. (Sept. 15th, 2018). Stanford Cancer Biology 41st Annual Retreat. San Jose, CA. (Oral presentation)

Tarangelo A, Magtanong L, Bieging-Rolett K, Li Y, Ye J, Attardi LD, Dixon, SJ. The p53-p21 pathway suppresses non-apoptotic cell death through metabolic rewiring. (June 25th, 2018). 2nd Annual Stanford ChEM-H Chemical/Biology Interface Retreat. Menlo Park, CA. (Poster presentation)

Tarangelo A. The adventure beyond your door: Reflections on life, cell death, and grad school. (Mar 1st, 2018). Presentation for approximately 400 prospective graduate students at the Stanford Biosciences Recruitment Welcome Breakfast. (Oral presentation)

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2017

Tarangelo A, & Dixon SJ. Turning to the dark side: p53 in cancer cell survival and metabolic adaptation. (Nov 17th, 2017). Stanford Biology Department Seminar Series. Stanford, CA. (Oral presentation)

Tarangelo A, Bieging-Rolett K, Li Y, Yi J, Attardi LD, Dixon SJ. The p53-p21 pathway suppresses non-apoptotic cell death through metabolic rewiring. (Sept 15th, 2017). Stanford Cancer Biology Program 40th Annual Conference. San Jose, California. (Poster presentation)

Tarangelo A & Dixon SJ. Turning to the dark side: The role of p53 in survival and metabolic adaptation. (May 30th, 2017). Stanford Cancer Biology Program Seminar (Oral presentation)

Tarangelo A & Dixon SJ. Investigating the role of p53 in non-apoptotic cell death.

 (Mar. 16th, 2017). Fusion Conference on Cell Death, Cell Stress, and Metabolism. Cancún, Mexico. (Oral presentation, selected for award) 

Tarangelo A & Dixon SJ. Death Metal: The role of p53 in ferroptosis. (Mar. 3rd, 2017). Presentation for incoming students at the Stanford Cancer Biology Recruitment Weekend. (Oral presentation)

2016

Tarangelo A & Dixon SJ. Investigating the role of p53 in non-apoptotic cell death. (Sept. 22nd, 2016). Stanford Cancer Biology Program 39th Annual Conference. San Jose, California. (Oral presentation, selected for award) 

2015

Tarangelo A & Dixon SJ. Investigating the role of p53 in ferroptosis. (Sept. 25th, 2015) Stanford Biology Department Seminar. (Oral presentation) 

 Conlon M, Tarangelo A, Ko P-J, Dixon SJ.  Regulation of ferroptosis by metabolic and signaling networks. (Sept. 16th, 2015) Cold Spring Harbor Meeting on Cell Death (Poster presentation)

2014

Tarangelo A, Lo N, Le L, Watson D, Viatour P.  Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. (Feb. 24th, 2014) Children’s Hospital of Philadelphia Discovery to Innovation Poster Day. (Poster presentation, selected for award)

2012

Tarangelo A, Kurzweil V, Oliver PM. Gastrointestinal microbiota do not significantly contribute to T cell activation or GI inflammation in Ndfip1-cKO mice. University of Pennsylvania 4th Annual Undergraduate Research Symposium, (Feb. 9th, 2012). (Poster presentation)

Teaching and Mentorship

2019

Mentor, Stanford Vice Provost for Graduate Education STEM Women Mentors Program

 Mentee: Julia Todderud

• Served as a mentor to a Stanford undergraduate interested in pursuing a STEM career. 

2018

Mentor to volunteer high school student

 Mentee: Edo Biluar

• Mentored a local high school volunteer in molecular biology techniques, data analysis and interpretation, and experimental design

Rotation Student Mentor, Dixon Laboratory

Mentee: Jason Rodencal, Cancer Biology Ph.D. Student

• Provided training in cell culture techniques, high-throughput drug screening, experimental design, and scientific communication.

2017

Mentor, Stanford Summer Research Program (SSRP)

Mentee: Myshal Morris, Undergraduate at Langston University, Amgen Scholar

• The Stanford Summer Research program provides research opportunities for undergraduates from small colleges or from backgrounds underrepresented in STEM

• Trained my mentee in scientific thinking, experimental design, wet lab techniques, and scientific communication

Rotation Student Mentor, Dixon Laboratory

Mentee: Tony Boutelle, Cancer Biology Ph.D. Student

• Provided training in laboratory techniques, experimental planning, and scientific communication

2016

Teaching Assistant, Cancer Biology 240: Molecular and Genetic Basis of Cancer

Professor Edward Graves

• Designed and graded class assignments, guided a weekly discussion section, and provided one-on-one instruction to 15 graduate students

Mentor, Vice Provost of Undergraduate Education Summer Research Program

Mentee: Carson Poltorack, Undergraduate at Stanford University

• Provided training in wet-lab techniques, experimental design, and scientific communication

2014-2017

Volunteer Teacher, Stanford Splash

• The Stanford Splash program invites high school students from across California to attend short classes (1-2 hours) taught by Stanford students.

• Designed and taught Splash classes on topics including cancer biology, epidemiology, biochemistry, and public speaking in Fall 2014, Spring and Fall 2015, Spring and Fall 2016, and Spring 2017.

Outreach and Leadership

2020-2023

Children’s Medical Center Research Institute Metabolism Journal Club Founder and Organizer

• Founded and organize a monthly journal club focusing on metabolism research at the Children’s Medical Center Research Institute (CRI) at UT Southwestern.

• Responsibilities include scheduling speakers, managing meetings and leading discussions.

• Meeting attended by 5 labs and 20+ trainees

2017-2018

Admissions Committee Student Member, Stanford Cancer Biology Program

• Chosen as  one of two student members of the admissions committee to evaluate applicants for admission to the Cancer Biology program for the 2018-2019 academic year. 

2016-2017

Program Representative, Stanford Biosciences Student Association (SBSA) Executive Committee

• Represented the interests of my classmates and advised the direction of SBSA programs and resources.

2015-2016                     

Social Activities Chair, Stanford Biosciences Student Association (SBSA) Executive Committee

• Planned monthly events for Stanford Biosciences graduate students to promote community building and student wellness.

2014-2017                     

Alumni Volunteer, Alumni Interviewer for the University of Pennsylvania

• Served as an alumni interviewer and conduct admissions interviews of high school students applying to the University of Pennsylvania.